α-AMY-α-娣€绮夐叾娴嬪畾璇曞墏鐩?EPS 搴曠墿娉?CNPG3 搴曠墿娉?
--鎬ユ€ц儼鑵虹値鐨勮瘖鏂寚鏍嘃/h3>
鏍锋湰绫诲瀷锛氭柊椴滄棤婧惰琛€娓呮垨灏挎恫
閫傜敤浠櫒锛氭湰璇曞墏鐩掗€傜敤浜庣粷澶у鏁颁富娴佺敓鍖栧垎鏋愪华
璇曞墏鐩掍紭鍔军/h4>
1.琛€灏垮悓妫€
2.閲囩敤IFCC鎺ㄨ崘鏂规硶锛屾彁楂樻姉骞叉壈鑳藉姏
3.绮惧瘑搴﹂珮锛孋V≤4%
5.璇曞墏瓒呴暱鏁堟湡24涓湀
6.鏍″噯鍝佸畾鍊兼函婧愯嚦GBW(E)090593
*鍙︽湁α-娣€绮夐叾(CNPG3搴曠墿娉?娴嬪畾璇曞墏鐩扅/p>
鎸囨爣绠€浠婞/h3>
α-娣€绮夐叾锛岀郴缁熷悕绉颁负1,4-α-D-钁¤仛绯栬憽鑱氱硸姘磋В閰讹紝鏄竴绉嶅唴鍒囩硸鑻烽叾骞挎硾鍒嗗竷浜庝汉浣撳斁娑插拰鑳拌剰涓紝鏄渶閲嶈鐨勬按瑙ｇ⒊姘村寲鍚堢墿鐨勯叾锛屽彲閫氳繃鑲惧皬鐞冩护杩囷紝鏄敮涓€鑳藉湪姝ｅ父鏃跺嚭鐜颁簬灏夸腑鐨勮娑查叾銆備富瑕佹潵婧愪簬鑳拌吅鍜岃叜鑵猴紝鐢辫偩鑴忔帓娉勩€傚綋鎬ユ€ц儼鑵虹値鏃讹紝琛€娓呬腑娣€绮夐叾杩呴€熷崌楂橈紝鎵€浠ヤ复搴婁笂涓昏鐢ㄤ簬鑳拌吅鐐庣殑杈呭姪璇婃柇銆侟/p>
妫€娴嬪師鐞咟/h3>
EPS 搴曠墿娉曪細α-娣€绮夐叾涓?alpha;-钁¤悇绯栬嫹閰跺伓鑱旓紝姘磋В鐗瑰紓鎬у簳鐗?,6-浜氫箼鍩?4-纭濆熀鑻厷-α-搴氱硸(4,6-ethylidene-G7PNP,EPS),浜х敓瀵?纭濆熀鑻厷锛屽-纭濆熀鑻厷鐢熸垚閫熺巼涓?alpha;-娣€绮夐叾鐨勬椿鎬ф垚姝ｆ瘮锛屽湪405nm娉㈤暱涓嬬敤閫熺巼娉曟娴嬨€侟/p>
涓村簥搴旂敤
- 褰撹儼鑵虹柧鐥呭挨鍏舵槸鎬ユ€ц儼鑵虹値鍙戠敓鏃讹紝浠庤儼绠＄澹佸強鑳版场涓€稿嚭鐨勮儼娣€绮夐叾鍙洿鎺ユ秷鍖栬儼鑵虹粍缁囥€傛紡鍑虹殑鑳版恫琚惛鏀跺叆琛€鑰岄殢灏夸腑鎺掑嚭銆傛晠琛€銆佸翱娣€绮夐叾鍧囧彲鍗囬珮锛屽鍏惰繘琛屾祴瀹氾紝鏄复搴婁笂璇婃柇鑳拌吅鐤剧梾甯哥敤鐨勬柟娉曘€侟/li>
- 涓浗鎬ユ€ц儼鑵虹値璇婃不鎸囧崡(2021)[1]涓寚鍑烘€ユ€ц儼鑵虹値鐨勮瘖鏂爣鍑嗗寘鎷互涓?椤癸細(1)涓婅吂閮ㄦ寔缁€х柤鐥汒(2)琛€娓呮穩绮夐叾鍜?鎴?鑴傝偑閰舵祿搴﹂珮浜庢甯镐笂闄愬€?鍊岥(3)鑵归儴褰卞儚瀛︽鏌ョ粨鏋滄樉绀虹鍚堟€ユ€ц儼鑵虹値褰卞儚瀛︽敼鍙樸€備笂杩?椤规爣鍑嗕腑绗﹀悎2椤瑰嵆鍙瘖鏂负鎬ユ€ц儼鑵虹値銆侟/li>
- 琛€娓呭拰灏挎恫涓殑α-娣€绮夐叾娲绘€у崌楂樺彲鎻愮ず鑵吅鐐庛€佽儼鑵虹値鐨勫瓨鍦ㄥ拰鑳拌吅闃诲銆?alpha;-娣€绮夐叾娲绘€ч檷浣庡彲瑙佷簬鑲濈値銆佽倽纭寲銆佽倽鐧屻€佸濞犳瘨琛€鐥囥€佹參鎬ц儼鑵虹値銆佹€ユ€ч厭绮句腑姣掔瓑[2]銆侟/li>
- 鎬ユ€ф湁鏈虹７鍐滆嵂涓瘨(acute organophosphorus pesticide poisoning, AOPP)鏄€ヨ瘖绉戞渶甯歌鐨勫嵄閲嶇棁涔嬩竴锛岃娓?alpha;-娣€绮夐叾姘村钩涓嶢OPP鐨勪弗閲嶇▼搴﹀拰棰勫悗瀵嗗垏鐩稿叧[3]銆侟/li>
閫傜敤绉戝
|
閫傜敤绉戝 |
瀵瑰簲鐥囩姸 |
|
娑堝寲鍐呯 |
鐢变簬α-AMY涓昏鏉ユ簮浜庤儼鑵哄拰鍞炬恫鑵猴紝娑堝寲鍐呯鍖荤敓缁忓父闇€瑕佹娴嬫偅鑰呰娓呬腑鐨?alpha;-AMY姘村钩锛屼互璇婃柇鎬ユ€ц儼鑵虹値銆佹參鎬ц儼鑵虹値銆佽儼鑵鸿偪鐦ょ瓑鑳拌吅鐤剧梾銆侟/p> |
|
鍐呭垎娉岀 |
α-AMY鐨勭洃娴嬩篃鍙敤浜庤瘎浼板唴鍒嗘硨鍔熻兘锛岀壒鍒槸涓庡斁娑茶吅鐩稿叧鐨勫姛鑳姐€侟/p> |
|
鎬ヨ瘖绉慄/strong> |
α-AMY妫€娴嬪彲浠ヤ綔涓烘€ユ€ц儼鑵虹値鍜屽叾浠栫揣鎬ョ姸鍐电殑鍒濇绛涙煡宸ュ叿 |
|
澶栫 |
鍦ㄦ秹鍙婅儼鑵烘垨闄勮繎鍣ㄥ畼鐨勬墜鏈墠鍜屽悗锛?alpha;-AMY鐨勬娴嬫湁鍔╀簬鐩戞祴鎵嬫湳鏁堟灉鍜屾仮澶嶆儏鍐点€侟/p> |
鍙傝€冩枃鐚?/h3>
[1] 涓崕鍖诲浼氬绉戝鍒嗕細鑳拌吅澶栫瀛︾粍, 涓浗鎬ユ€ц儼鑵虹値璇婃不鎸囧崡(2021). 涓崕娑堝寲澶栫鏉傚織, 2021(07): p. 730-739.
[2] 寮犲鑻 and 鏉ㄥ箍瀹? α-娣€绮夐叾妫€娴嬫柟娉曞強鍏跺簲鐢? 鐢熺墿宸ョ▼瀛︽姤, 2023. 39(3): p. 898-911.
[3] Jannat, F., et al., Serum amylase as a prognostic marker of organophosphate poisoning. Journal of injury & violence research, 2021. 13 2.
鎸囧崡鍏辫瘑
