BMG-β2-寰悆铔嬬櫧娴嬪畾璇曞墏鐩?鑳朵钩鍏嶇柅姣旀祳娉?
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璇曞墏鐩掍紭鍔军/h4>
1.鑳朵钩鍏嶇柅姣旀祳娉曪紝鎻愰珮鐏垫晱搴﹀拰鐗瑰紓鎬?/p>
2.绮惧瘑搴﹂珮锛孋V≤5%
3.閫氳繃璁剧疆绋€閲婂弬鏁帮紝鍙姤鍛婅寖鍥村锛?锝?60mg/L
鎸囨爣绠€浠婞/h3>
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妫€娴嬪師鐞咟/h3>
浜鸿娓呮牱鏈腑鐨?beta;2-MG涓庤瘯鍓備腑閫傞噺鐨勭壒寮傛€ф姉浣撶粨鍚堬紝褰㈡垚涓嶆憾鎬х殑鍏嶇柅澶嶅悎鐗╋紝浣垮弽搴旀恫鍚稿厜搴︽敼鍙橈紝鍦ㄦ姉浣撻噺涓€瀹氱殑鏉′欢涓嬶紝鍚稿厜搴︾殑鏀瑰彉涓庝汉琛€娓呮牱鏈腑鐨?beta;2-MG鍚噺鎴愭鐩稿叧銆侟/p>
涓村簥搴旂敤
- 琛€β2-MG鍙嶆槧鑲惧皬鐞冩护杩囧姛鑳斤紝鏄棭鏈熻瘖鏂偩灏忕悆鐥呭彉鐨勬晱鎰熸寚鏍囥€傝娓?beta;-MG姣擟r鑳芥洿濂藉湴浼拌GFR鍙樺寲銆傚綋GFR涓害鏀瑰彉鏃讹紝娴嬪畾琛€β2-MG 姣擟r鏇存晱鎰熴€佸噯纭紝鏄棭鏈熻瘖鏂偩灏忕悆鐥呭彉鐨勬晱鎰熸寚鏍嘃span style="color:hsl(212,80%,42%);">[1]銆侟/li>
- 灏?beta;2-MG鏄瘎浠疯繎绔偩灏忕鍔熻兘鐨勬晱鎰熸寚鏍囷紝骞朵笖鑳藉弽鏄犺繎绔偩灏忕鎹熶激鐨勭▼搴?span style="color:hsl(212,80%,42%);">[2]銆傚翱β2-MG鍙敤浜庣硸灏跨梾鑲捐剰鐤剧梾(DKD)鑲惧皬绠″彈绱殑鏃╂湡绛涙煡銆備腑鍗庡尰瀛︿細鍐呭垎娉屽鍒嗕細2015骞村彂甯冪殑銆婁腑鍥芥垚浜虹硸灏跨梾鑲捐剰鐥呬复搴婅瘖鏂殑涓撳鍏辫瘑銆婞span style="color:hsl(212,80%,42%);">[3]鎸囧嚭锛屾帹鑽愬G3a锝?A1鏈烡KD鎮ｈ€咃紝鍗冲翱鐧借泲鐧介槾鎬х殑DKD鎮ｈ€咃紝杩涜鑲惧皬绠″彈绱殑鏃╂湡绛涙煡;绛涙煡鎸囨爣鍖呮嫭灏挎恫β2-MG锛屾帓闄ゅ奖鍝嶅洜绱犲悗渚濇嵁2锝?娆¤繘琛岀粨鏋滃垽瀹氥€侟/li>
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- 灏?beta;2-MG鍙敤浜庤偩鑴忕梾鐨勯壌鍒瘖鏂笌鍒嗗瀷銆備复搴婁笂鑲濊偩缁煎悎寰?HRS)鍜屾€ユ€ц偩灏忕鍧忔(ATS)闅句互鍖哄埆锛屾祴瀹氬翱β2-MG鍙綔鍑洪壌鍒紝鍗矵RS 鎮ｈ€呭翱β2-MG(0.155±0.043)mg/L鏄捐憲浣庝簬ATS(3.286锝?00.504)mg/L銆傝繖鏄洜涓 β2 -MG鏄綆鍒嗗瓙鐗╄川锛屼粠鑲惧皬鐞冩护杩囧悗锛屽叏閮ㄨ杩戞洸鑲惧皬绠￠噸鍚告敹锛屽綋鑲惧皬绠″潖姝绘椂锛屽垯閲嶅惛鏀跺噺灏戯紝浣垮翱β2-MG 鏄捐憲澧炲姞銆傚湪鎬ユ€ц偩鐩傝偩鐐庢椂锛屽洜鑲捐剰鍙楃疮锛屽翱β2-MG鍗囬珮锛岃€屽崟绾粏鑿屾€ц唨鑳辩値鍒欐甯符鎱㈡€ц偩鐩傝偩鐐庡彂浣滄湡鎮ｈ€呭翱β2-MG 鏄庢樉鍗囬珮锛岃€岄潪鍙戜綔鏈熷垯姝ｅ父锛屾晠浠ヨ祫閴村埆銆傝偩鐐庢€ц偩鐥呫€佷箼鍨嬭倽鐐庣浉鍏虫€ц偩鐐庡強浣庤ˉ浣撴€ц偩鐐庢偅鑰呭翱β2-MG鍧囨槑鏄惧崌楂樸€傚洜姝わ紝灏?beta;2-MG瀵硅偩鐥呴壌鍒瘖鏂笌涓村簥鍒嗗瀷閲嶈鍙傝€冧环鍊稽span style="color:hsl(212,80%,42%);">[2]銆侟/li>
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[7] 琚佹娆?鏉ㄥ皯鍗?楂樺繝鐖?绛? 灏挎恫β2寰悆铔嬬櫧瀵?鍨嬬硸灏跨梾瑙嗙綉鑶滅梾鍙橀娴嬩环鍊肩殑鍓嶇灮鎬х爺绌禰J]. 涓浗绯栧翱鐥呮潅蹇?2018,26(3):201-205.
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[12] 琚佸嚡鏅?濮滄檽鑹? 琛€娓?beta;2寰悆铔嬬櫧鍦ㄥ績鑴戣绠＄柧鐥呬腑鐨勭爺绌惰繘灞昜J]. 瀹炵敤鑰佸勾鍖诲,2021,35(8):879-882.
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鎸囧崡鍏辫瘑
